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Dysbiosis

February 13, 2004

Dear Parents

Some interesting developments recently in our management
programme, particularly in the area of Dysbiosis (abnormal
bacterial and/or fungal growth in the intestine.

Approximately 80% of Autistic children have diarrhoea, 10%
have constipation and about 10% have normal stool
consistency.

We find that the majority of children with chronic
diarrhoea have overgrowth of Clostridium Difficile and
usually Candida as well, and

The majority of children with constipation have an
overgrowth of Bacteroides.

These 'bugs' produce toxins (peptides) which leak through
the bowel wall into the bloodstream and affect the function
of the brain.

We have found that identifying and eradicating these
bacteria and yeasts makes a huge difference to a child's
progress.

Interestingly, a high percentage of adults with Irritable
Bowel Syndrome (IBS) have an overgrowth of Clostridium
Difficile and also benefit from eradication therapy.

More information is available on our website under Autism
and Dysbiosis.

Please call or email if you have any questions to ask.

Best wishes
David Patterson MD